Antineoplastic effect of chlorpromazine in chemical carcinogenesis in the hamster cheek pouch.
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چکیده
منابع مشابه
Spontaneous differentiated squamous cell carcinoma of cheek pouch in a Syrian hamster
A 2-year-old male hamster was presented because of left facial swelling and salivation. Necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. In histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. Vacoulation o...
متن کاملDetection of Ki-ras messenger RNA in normal and chemically transformed hamster oral keratinocytes.
The cheek pouch of the Syrian hamster is an excellent model for the experimental study of oral carcinogenesis. The carcinogenic chemical 7,12-dimethylbenz[a]anthracene consistently produces epidermoid carcinomas in the cheek pouch of the Syrian hamster, giving rise to characteristic histopathological lesions in a time-dependent manner. We now present experimental evidence that c-Ki-ras mRNA can...
متن کاملEffects of dimethyl sulfoxide on dimethylbenzanthracene-induced carcinogenesis in the hamster cheek pouch.
The studies demonstrated that the use of dimethyl sulfoxide (DMSO) as a vehicle for dimethylbenzanthracene in the produc tion of experimental tumors in the hamster cheek pouch, sig nificantly reduced the latent period for tumor production when compared to the usual mineral oil vehicle. No systemic or local changes could be attributed to the DMSO itself, and the mor phology of induced tumors was...
متن کاملEffects of Dimethyl Sulfoxide on Dimethylbenzanthraceiie-induced Carcinogenesis in the Hamster Cheek Pouch1
The studies demonstrated that the use of dimethyl sulfoxide (DMSO) as a vehicle for dimethylbenzanthracene in the produc tion of experimental tumors in the hamster cheek pouch, sig nificantly reduced the latent period for tumor production when compared to the usual mineral oil vehicle. No systemic or local changes could be attributed to the DMSO itself, and the mor phology of induced tumors was...
متن کامل[Histologic study on impeding leukoplakia carcinogenesis of golden hamster cheek pouch about Erigeron breviscapus (Vant) Hand-Mazz].
OBJECTIVE To observe the effect of Erigeron breviscapus (Vant) Hand Mazz (HEr) in impeding oral leukoplakia carcinogenesis, and to seek effective Chinese herb medicine that can impede precarcinoma of oral mucosas. METHODS 132 golden hamsters were randomly divided into model group (60 animals), HEr group (60 animals), and control group 12 animals. Salley's leukoplakia carcinogenesis model of g...
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ورودعنوان ژورنال:
- Cancer research
دوره 32 9 شماره
صفحات -
تاریخ انتشار 1972